Aetion® Activate streamlines the preparation of analysis-ready datasets and enables advanced analytics.
NEW YORK, August 21, 2025 — Aetion®, a Datavant Company, the global leader in real-world evidence (RWE) technology and analytics, today announced the launch of Activate, a complete development solution that combines low-code tools with a hosted coding environment to help users efficiently define measures, transform complex datasets, and execute advanced analytics in a reproducible, audit-ready workflow. This capability enables life sciences organizations and data companies to scale their evidence generation strategies with end-to-end data management that streamlines the labor-intensive, error-prone steps of data preparation, freeing teams to focus on the high-value analyses that inform drug development.
Together, Datavant and Aetion are addressing a critical challenge facing healthcare companies, life sciences organizations, and data vendors. It is widely acknowledged that an overwhelming majority of the time in data analysis projects is spent discovering, preparing, and enriching data to be analysis-ready. Activate allows users to recover this time with reusable, customizable point-and-click algorithms that streamline the time-consuming process of data cleaning and preparation. In parallel, Datavant Connect powered by AWS Clean Rooms accelerates cloud-first insight generation by enabling data discovery, assessment, and feasibility of third-party datasets more efficiently within an organization’s own secure research environment.
Designed for a diverse set of users—including real-world data analysts, biostatisticians, data scientists, and data providers—Activate’s built-in UI guardrails and centrally managed definitions support the creation of consistent, analysis-ready datasets. When deeper analysis is needed, technical users can transition seamlessly into a hosted IDE, with full audit trails and versioning to ensure transparency and reproducibility.
“Bringing Aetion and Datavant together unlocks a new era of possibility for evidence generation that is streamlined and actionable,” said Sailu Challapalli, SVP of Life Sciences Product at Datavant. “Activate exemplifies how our combined capabilities can accelerate the path from raw data to actionable evidence, enabling life sciences organizations and partners to generate insights more efficiently, with greater rigor, and at unprecedented scale.”
“Our goal is to simplify the complex so teams can focus on the analysis that matters,” said Jeremy Rassen, Co-founder of Aetion. “By uniting cohort creation, variable definition, and data management into one intuitive environment, we enable teams to get to high-quality outputs faster and with greater confidence."
Activate is fully integrated with Aetion® Substantiate, the industry-leading application for decision-grade descriptive and causal analyses, and the broader AEP ecosystem. This integration ensures that data prepared in Activate maintains the highest standards of scientific rigor while enabling collaboration across different user types.
For more information or to request a demo, visit aetion.com/activate or contact us here.
About Aetion
Aetion®, a Datavant Company, is a global leader in healthcare technology that delivers real-world evidence (RWE) solutions to biopharmaceutical companies, medical device manufacturers, payers, and regulators. Powered by Aetion Evidence Platform®, Aetion applies advanced causal inference, rigorous epidemiologic methods, and purpose-built AI to transform complex healthcare data into transparent, reliable evidence on the safety, effectiveness, and value of medical treatments. Now part of Datavant, Aetion is part of an end-to-end solution that makes real-world evidence more actionable and scalable, informing decisions on which treatments work best, for whom and when. Learn more at aetion.com and follow us on LinkedIn.
Media Contact:
Lynn Shepherd
Head of Corporate Communications, Datavant
lynn.shepherd@datavant.com